|
TMPY-00539
|
GSTA1 Protein, Human, Recombinant (His)
glutathione S-transferase alpha 1,GTH1,GST2
|
Human
|
HEK293 Cells
|
|
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno... |
|
TMPY-04408
|
CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)
calcium/calmodulin-dependent protein kinase II beta,CAM2...
|
Human
|
Baculovirus Insect Cells
|
|
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in prostate cancer cells ability to escape apoptosis under androgen ablation and facilitate the progression of prostate cancer cells to an androgen independent state. As a multifunctional protein kinase, the loss of activity may play a critical role in initiating the changes leading to... |
|
TMPY-02223
|
GSTM2 Protein, Human, Recombinant (His)
GSTM2-2,GTHMUS,glutathione S-tran...
|
Human
|
E. coli
|
|
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si... |
|
TMPJ-00690
|
PGDS Protein, Human, Recombinant
Glutathione-Requiring Prostaglandin D Synthase,PGDS,Glutathi...
|
Human
|
E. coli
|
|
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop... |
|
TMPY-04452
|
AMPK (G1/B2/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β2, γ1)
|
Human
|
Baculovirus Insect Cells
|
|
AMPK (G1/B2/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619&O43741&Q13131-1. |
|
TMPY-02787
|
Aconitase 2 Protein, Mouse, Recombinant (His & GST)
Aco-2,D10Wsu183e,aconitase 2, mitochondria...
|
Mouse
|
Baculovirus Insect Cells
|
|
Aconitase 2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 110 kDa and the accession number is Q99KI0. |
|
TMPY-02545
|
Aconitase 2 Protein, Human, Recombinant (His & GST)
ACONM,ICRD,aconitase 2, mitochondrial
|
Human
|
Baculovirus Insect Cells
|
|
Aconitase 2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 110 kDa and the accession number is Q99798. |
|
TMPY-01762
|
IGF2BP-2 Protein, Human, Recombinant (His & GST)
insulin-like growth factor 2 mRNA binding protein <...
|
Human
|
Baculovirus Insect Cells
|
|
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa c... |
|
TMPH-02069
|
Secretogranin-2 Protein, Human, Recombinant (GST & His)
|
Human
|
E. coli
|
|
Secretogranin-2 Protein, Human, Recombinant (GST & His) is expressed in E. coli. |
|
TMPY-03462
|
15 Lipoxygenase 2 Protein, Human, Recombinant (His & GST)
ALOX15B,arachidonate 15-lipoxygenase, type B,15-LOX-2
|
Human
|
Baculovirus Insect Cells
|
|
15 Lipoxygenase 2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 103.7 kDa and the accession number is AAH35217.1. |
|
TMPJ-01035
|
UBE2G2 Protein, Human, Recombinant (GST)
Ubiquitin-Conjugating Enzyme E2 G2,Ubiquit...
|
Human
|
E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked ... |
|
TMPY-02957
|
DYDC2 Protein, Human, Recombinant (GST)
DPY30 domain containing 2
|
Human
|
E. coli
|
|
DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family inv... |
|
TMPH-02005
|
RRAS2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
RRAS2 Protein, Human, Recombinant (GST) is expressed in E. coli. |
|
TMPY-04393
|
CSNK2A2 Protein, Human, Recombinant (His & GST)
casein kinase 2, alpha prime polypeptide,CK2
|
Human
|
Baculovirus Insect Cells
|
|
CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69 kDa and the accession number is P19784. |
|
TMPH-01557
|
ILF2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. ILF2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 70.1 kDa and the acce... |
|
TMPH-01511
|
GLO2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. |
|
TMPH-01927
|
PSMB2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
PSMB2 Protein, Human, Recombinant (GST) is expressed in E. coli. |
|
TMPY-01203
|
RP2 Protein, Human, Recombinant (GST)
DELXp11.3,RP2,NME10,KIAA0215,NM23...
|
Human
|
Baculovirus Insect Cells
|
|
XRP2, also known as Protein XRP2 and RP2, is a member of the TBCC (tubulin cofactor C) family and contains one C-CAP/cofactor C-like domain. This protein is encoded by the RP2 gene in humans. XRP2 stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. XRP2 acts as guanine nucleotide dissociation inhibitor for ARL3. Defects in RP2 gene are the cause of retinitis pigmentosa type 2 (RP2), also known as X-linked retinitis pigmentosa 2 (XLRP-2). It leads to degene... |
|
TMPH-01776
|
HMGN2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. HMGN2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 36.4 kDa and the accession number is P05204. |
|
TMPJ-01221
|
UBE2J2 Protein, Human, Recombinant (GST)
NCUBE-2,UBE2J2,Ubiquitin-Conjugat...
|
Human
|
E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 J2 (UBE2J2) belongs to the ubiquitin-conjugating enzyme family. UBE2J2 is involved in the ubiquitiantion. UBE2J2 located in the membrane of the endoplasmic reticulum, catalyzes the covalent attachment of ubiquitin to other proteins. UBE2J2 may play a important role in the selective degradation of misfolded membrane protein from the endoplasmic reticulum. |
|
TMPY-02298
|
ACYP2 Protein, Human, Recombinant (GST)
ACYM,acylphosphatase 2, muscle type,ACYP
|
Human
|
E. coli
|
|
Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 a... |
|
TMPY-03399
|
KLHL2 Protein, Human, Recombinant (GST)
kelch like family member 2,ABP-KELCH,MAYVEN,KLHL
|
Human
|
E. coli
|
|
KLHL2 (Kelch Like Family Member 2) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. KLHL2 contains 1 BTB (POZ) domain and 6 Kelch repeats. It is widely expressed in the brain, esophagus, and other tissues. KLHL2 gene has been proposed to participate in intracellular protein transportation. KLHL2 is expected to have molecular functions such as transporter activity, actin-binding, and protein binding. KLHL2 localizes in various compartments such as actin cytoske... |
|
TMPJ-01157
|
LACTB2 Protein, Human, Recombinant (GST)
β-Lactamase-Like Protein 2,LACTB2,Beta-Lac...
|
Human
|
E. coli
|
|
β-Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family. LACTB2 is 288 amino acids long with 8 zinc-binding domains. The LACTB2 gene is expressed at high levels and annotates structural defects or features in 4 cDNA clones. LACTB2 proteins are expected to have hydrolase activity and metal ion-binding functions. LACTB2 protein is found to localize in mitochondrion. Other functions of LACTB2 is yet unknown. |
|
TMPH-01868
|
FUCA2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. FUCA2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9BTY2. |
|
TMPH-01787
|
NCBP2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
NCBP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.9 kDa and the accession number is P52298. |
|
TMPY-01306
|
DNMT2 Protein, Human, Recombinant (GST)
PUMET,RNMT1,tRNA aspartic acid methyltransferase 1,MHSAIIP,D...
|
Human
|
Baculovirus Insect Cells
|
|
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evolution and contain all of the signature motifs of DNA (cytosine-5)-methyltransferases. It contains all 10 sequence motifs that are conserved among m(5)C MTases, including the consensus S:-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide, and its structure... |
|
TMPH-02846
|
BICD2 Protein, Mouse, Recombinant (GST)
Bicd2,Kiaa0699,Bic-D 2,Protein bicaudal D ...
|
Mouse
|
E. coli
|
|
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (... |
|
TMPY-01775
|
AIM2 Protein, Human, Recombinant (GST)
absent in melanoma 2,PYHIN4
|
Human
|
Baculovirus Insect Cells
|
|
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytoplasmic DNA by means of its oligonucleotide/oligosaccharide-binding domain and interacts with ASC (apoptosis-associated speck-like protein containing a CARD) through its pyrin domain to activate caspase-1. In response to foreign cytoplasmic DNA, AIM2 forms an inflammasome, resulting... |
|
TMPH-01780
|
SCP2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
SCP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.4 kDa and the accession number is P22307. |
|
TMPY-04681
|
CHEK2 Protein, Human, Recombinant (GST)
CDS1,HuCds1,checkpoint kinase 2,hCds1,LFS2...
|
Human
|
Baculovirus Insect Cells
|
|
CHEK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 88.1 kDa and the accession number is O96017-1. |
|
TMPY-04544
|
MEK2 Protein, Human, Recombinant (GST)
mitogen-activated protein kinase kinase 2,FLJ2<...
|
Human
|
Baculovirus Insect Cells
|
|
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ... |
|
TMPY-04539
|
ERK2 Protein, Human, Recombinant (GST)
ERT1,ERK,PRKM1,ERK-2,p41,p41mapk,PRKM2,ERK...
|
Human
|
Baculovirus Insect Cells
|
|
ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 67 kDa and the accession number is P28482-1. |
|
TMPH-02025
|
RPA2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
RPA2 Protein, Human, Recombinant (GST) is expressed in E. coli. |
|
TMPH-01637
|
Mammaglobin-A/SCGB2A2 Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
Mammaglobin-A/SCGB2A2 Protein, Human, Recombinant (GST) is expressed in E. coli. |
|
TMPY-04387
|
AKT2 Protein, Human, Recombinant (His & GST)
RAC-β,RAC-BETA,HIHGHH,PKBBETA,PKBβ,PRKBB,PKBB,v-akt murine t...
|
Human
|
Baculovirus Insect Cells
|
|
AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer progressions, through modulating angiogenesis, tumor growth, and cell migration, invasion, metastasis, and chemoresistance. Among all three isoforms, AKT2 is most related to cancer cell invasion, metastasis, and survival. Amplification and overexpression of AKT2 have been shown in ma... |
|
TMPJ-01138
|
UBE2S Protein, Human, Recombinant (GST)
UBE2S,Ubiquitin-Conjugating Enzyme E2-...
|
Human
|
E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiqui... |
|
TMPH-02966
|
UPK2 Protein, Mouse, Recombinant (GST & His)
|
Mouse
|
E. coli
|
|
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM. UPK2 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 40.8 kDa and the accession number is P38575. |
|
TMPH-01881
|
PARP2 Protein, Human, Recombinant (GST & His)
|
Human
|
Baculovirus Insect Cells
|
|
PARP2 Protein, Human, Recombinant (GST & His) is expressed in Baculovirus insect cells with N-GST and C-6xHis tag. The predicted molecular weight is 92.8 kDa and the accession number is Q9UGN5. |
|
TMPH-01307
|
EIF4A2 Protein, Human, Recombinant (GST)
EIF4A2,eIF4A-II,Eukaryotic initiation factor 4A-II,...
|
Human
|
E. coli
|
|
EIF4A2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 73.4 kDa and the accession number is Q14240. |
|
TMPY-00522
|
KLC2 Protein, Human, Recombinant (His & GST)
kinesin light chain 2
|
Human
|
Baculovirus Insect Cells
|
|
KLC2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 96.8 kDa and the accession number is Q9H0B6-1. |
|
TMPY-04764
|
PCK2 Protein, Human, Recombinant (His & GST)
PEPCK-M,PEPCK2,PEPCK,phosphoenolpyruvate carboxykin...
|
Human
|
Baculovirus Insect Cells
|
|
PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabolic switch and the maintenance of TICs in prostate cancer. PCK2 is a potential therapeutic target for aggressive prostate tumors. |
|
TMPY-04571
|
ERK2 Protein, Mouse, Recombinant (His & GST)
PRKM2,C78273,mitogen-activated protein kin...
|
Mouse
|
Baculovirus Insect Cells
|
|
ERK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.1 kDa and the accession number is P63085. |
|
TMPH-01479
|
H2AFX Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
H2AFX Protein, Human, Recombinant (GST) is expressed in E. coli. |
|
TMPY-04562
|
GRK2 Protein, Human, Recombinant (His & GST)
β,adrenergic, beta, receptor kinase 1
|
Human
|
Baculovirus Insect Cells
|
|
G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, integrative role in signal transduction cascades. GRK2 can phosphorylate a growing number of non-GPCR substrates and associate with a variety of proteins related to signal transduction, thus suggesting that this kinase could also have diverse 'effector' functions. GRK2 has been repor... |
|
TMPY-02386
|
PTP4A2 Protein, Human, Recombinant (GST)
HNMT-S2,PRL-2,HNMT-S1,protein tyrosine pho...
|
Human
|
E. coli
|
|
PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeu... |
|
TMPY-01711
|
Serpin B2 Protein, Human, Recombinant (GST)
PAI,serpin peptidase inhibitor, clade B (ovalbumin), member ...
|
Human
|
Baculovirus Insect Cells
|
|
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.SerpinB2, also known as Plasminogen activator inhibitor 2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor and PAI2, is a cytoplasm protein that belongs to the serpin fa... |
|
TMPJ-00985
|
UBE2A Protein, Human, Recombinant (GST, His)
RAD6A,HR6A,Ubiquitin-Protein Ligase A,UBE2A,hHR6A,U...
|
Human
|
E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is re... |
|
TMPY-04458
|
TRIB2 Protein, Human, Recombinant (His & GST)
TRIBBLE,tribbles pseudokinase 2,TRIB2,C5FW...
|
Human
|
Baculovirus Insect Cells
|
|
Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems and physiological processes, including development, together with their potential involvement in diabetes and cancer, has generated considerable interest in these proteins. Tribbles have been reported to regulate the activation of some intracellular signalling pathways with roles e... |
|
TMPJ-01053
|
UBE2I Protein, Human, Recombinant (GST)
SUMO-Protein Ligase,Ubiquitin-Conjugating Enzyme E2...
|
Human
|
E. coli
|
|
SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin homologue, Small Ubiquitin-Like Modifier 1 (SUMO-1). The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging. |
|
TMPJ-01047
|
UBE2H Protein, Human, Recombinant (GST)
UBE2H,UbcH2,Ubiquitin-Conjugating Enzyme E...
|
Human
|
E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in ... |
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